Beauty Blog

December 22, 2023

10 Glutathione Injection Side Effects You Should Know About

glutathione injection side effects - top 10

Today, we shed light on the topic of glutathione injection side effects, a trend that has gained attention in the pursuit of skin perfection. While these injections promise numerous benefits, it’s crucial to be aware of potential side effects to make educated decisions about your skincare routine.

Jump to a specific side effect:

  1. Allergic Reactions
  2. Skin Sensitivity
  3. Gastrointestinal Distress
  4. Diarrhea
  5. Headaches
  6. Skin Flushing
  7. Dizziness
  8. Liver Enzyme Changes
  9. Kidney Function
  10. Individual Variation
  11. BONUS: Skin Whitening

#1 Allergic Reactions (Low risk)

Just like some folks are allergic to peanuts, a few might react to glutathione injections. This can range from a bit of itching and red bumps to more serious stuff like swelling and trouble breathing. It’s like your body’s saying, “Hey, I’m not a fan of this!”

Allergic reactions to glutathione injections can happen due to hypersensitivity to the compound or other additives in the injection solution. The immune system overreacts, leading to symptoms like itching, hives, swelling, or difficulty breathing.

#2 Skin Sensitivity (moderate risk)

Sometimes, the spot where you got the shot can get red or irritated. Think of it like the skin’s grumpy way of saying, “What’s this poking me?” Skin sensitivity or irritation at the injection site may result from the needle’s insertion and the chemical solution. The skin reacts to this intrusion, leading to redness or discomfort.

#3 Gastrointestinal Distress (low to moderate risk)

Your stomach might get a bit upset, leading to nausea or a queasy feeling. Digestive issues, including nausea, vomiting, and abdominal discomfort, may arise. Usually, food can help alleviate these symptoms.

Gastrointestinal distress, such as nausea and abdominal discomfort, can occur as a response to the chemical composition of glutathione or its effect on the stomach lining.

#4 Diarrhea (low to moderate risk)

The introduction of glutathione may affect the natural balance of bacteria and other elements in your gut, known as the gut microbiome. This disruption can lead to gastrointestinal upset, including increased bowel movements or loose stools, commonly known as diarrhea.

Diarrhea often occurs when the contents of the gastrointestinal tract are moved along more quickly than usual, or when the intestine absorbs less water, leading to loose, watery stools.

#5 Headaches (low to moderate risk)

Headaches or migraines can be triggered, especially in sensitive individuals. When you receive a glutathione injection, your body encounters a high concentration of this powerful antioxidant. This sudden increase can trigger various responses as your body adjusts to the new levels.

Glutathione can influence blood vessels, leading to their dilation (widening). When blood vessels in the brain widen, they can stimulate the surrounding nerves, leading to pain or the throbbing sensation often associated with headaches.

#6 Skin Flushing (low risk)

Temporary skin flushing or redness may occur after injections. Glutathione injections widen the blood vessels and that increases blood flow to the area, which can make the skin appear red or flushed. It’s similar to the natural redness you see when you blush, where increased blood flow leads to a temporary change in skin color.

#7 Dizziness (low risk)

Some people may experience dizziness or lightheadedness. One of the primary reasons for dizziness following a glutathione injection could be changes in blood pressure. When blood pressure drops, less blood and oxygen may reach the brain, leading to feelings of lightheadedness or dizziness. It’s like when you stand up too quickly and feel momentarily unsteady.

#8 Liver Enzyme Changes (low to moderate risk)

Prolonged use of glutathione injections can lead to elevated liver enzymes, a sign that the liver is working harder than usual. They are proteins that speed up chemical reactions in the liver. They play a vital role in metabolizing substances like glutathione.

In some cases, it might indicate that the liver is experiencing difficulty in processing the glutathione, potentially leading to mild inflammation or stress on the liver cells.

#9 Kidney Function (low to moderate risk)

The kidneys are vital organs that filter waste products, excess water, and other impurities from the blood. These wastes are then excreted in the urine. Prolonged or frequent exposure to high levels of glutathione may increase the workload on the kidneys, as they continually filter these substances from the blood.

#10 Individual Glutathione Injection Side Effects

The chance of experiencing side effects varies as much as our personal stories. Genetics plays the master role, significantly influencing how we metabolize and react to glutathione. Those with existing health quirks, especially involving the liver or kidneys, might find themselves more sensitive to these injections.

Age and gender add their twists. And let’s not forget the details of our lifestyles – diet, exercise, and habits like smoking or sipping wine – all adding more complications to glutathione therapy.

The frequency and dosage of the injections matter a lot, too – it’s all about finding the right balance. Everyone’s experience is different: while some people sail through without any hiccups, others might need to navigate side effects that can range from being a minor annoyance to more serious concerns.

In a nutshell, other glutathione injection side effects could include fatigue, mood swings, appetite changes, muscle discomfort, sleep disturbances, immune and hormonal shifts, and blood sugar level fluctuations.

BONUS: Skin Whitening (high risk)

Glutathione injections can lighten your skin, which is a side effect, not their main purpose. They work by affecting melanin, the substance that colors our skin, hair, and eyes. Usually, this lightening becomes noticeable after about 10 sessions, but it varies from person to person.

As an antioxidant, glutathione is great at fighting off harmful elements in our skin, which helps reduce dark spots and evens out skin tone.


At 7 Derma Center, we prioritize your well-being above all else. We encourage you to consult with our experienced professionals who can provide personalized recommendations and guidance to prevent glutathione injection side effects, ensuring your safety and satisfaction.

In your pursuit of beauty and wellness, knowledge is your greatest asset. Stay informed, make thoughtful choices, and trust 7 Derma Center to support you on your journey to radiance.

Glutathione benefits & skin whitening ,


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7 Derma Clinic is an Aesthetic clinic where professionals with more than 20 years of experience are taking care of your appearance. Our mission is to bring more beauty into your wold and show you how perfect you can be in our imperfect world.

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